问题原因
尝试开启Charles-Proxy-macOS Proxy 时 提示：
Charles cannot configure your proxy settings while it is on a read-only volume. Perhaps you are running Charles from the disk image? If so, please copy Charles to the Applications folder and run it again. Otherwise please ensure that Charles is running on a volume that is read-write and try again.
一切和正常情况一样，但是无法进行代理。
问题排查
查阅有关文档，说是 没有正常安装导致，重装还是未解决。
解决方法
在Mac终端中输入
sudo chown -R root "/Applications/Charles.app/Contents/Resources"
sudo chmod -R u+s "/Applications/Charles.app/Contents/Resources"
重启Charles，完美解决。over~ 又可以愉快地玩耍了。